TY - JOUR AU - Acosta Lopez, Manuel J AU - Trevisson, Eva AU - Canton, Marcella AU - Vazquez-Fonseca, Luis AU - Morbidoni, Valeria AU - Baschiera, Elisa AU - Frasson, Chiara AU - Pelosi, Ludovic AU - Rascalou, Bérengère AU - Desbats, Maria Andrea AU - Alcázar-Fabra, María AU - Ríos, José Julián AU - Sánchez-García, Alicia AU - Basso, Giuseppe AU - Navas, Placido AU - Pierrel, Fabien AU - Brea-Calvo, Gloria AU - Salviati, Leonardo PY - 2019 DO - 10.1155/2019/3904905 UR - http://hdl.handle.net/10668/14362 T2 - Oxidative medicine and cellular longevity AB - Coenzyme Q (CoQ), a redox-active lipid, is comprised of a quinone group and a polyisoprenoid tail. It is an electron carrier in the mitochondrial respiratory chain, a cofactor of other mitochondrial dehydrogenases, and an essential antioxidant. CoQ... LA - en KW - Adenosine Triphosphate KW - Amino Acid Sequence KW - Animals KW - CRISPR-Cas Systems KW - HEK293 Cells KW - Humans KW - Mitochondria KW - Mutagenesis, Site-Directed KW - Protein Isoforms KW - Protein Structure, Tertiary KW - Reactive Oxygen Species KW - Sequence Alignment KW - Ubiquinone KW - Vanillic Acid TI - Vanillic Acid Restores Coenzyme Q Biosynthesis and ATP Production in Human Cells Lacking COQ6. TY - research article VL - 2019 ER -