TY - JOUR AU - Mostaza, José M AU - Suárez-Fernández, Carmen AU - Cosín-Sales, Juan AU - Gómez-Huelgas, Ricardo AU - Brotons, Carlos AU - Araujo, Francisco Pestana AU - Borrayo, Gabriela AU - Ruiz, Emilio AU - VULCANO investigators PY - 2022 DO - 10.1186/s12872-022-03013-w UR - http://hdl.handle.net/10668/20264 T2 - BMC cardiovascular disorders AB - Cardiovascular (CV) polypills are a useful baseline treatment to prevent CV diseases by combining different drug classes in a single pill to simultaneously target more than one risk factor. The aim of the present trial was to determine whether the... LA - en KW - Cardiovascular disease KW - Cardiovascular risk factors KW - Fixed-dose combination KW - Non-inferiority trial KW - Polypill KW - Primary prevention KW - Humans KW - Antihypertensive Agents KW - Cholesterol, LDL KW - Drug Combinations KW - Cardiovascular Diseases KW - Cholesterol KW - Hydroxymethylglutaryl-CoA Reductase Inhibitors TI - Safety and efficacy of a cardiovascular polypill in people at high and very high risk without a previous cardiovascular event: the international VULCANO randomised clinical trial. TY - research article VL - 22 ER -