TY - JOUR AU - Paschalis, Alec AU - Welti, Jonathan AU - Neeb, Antje J AU - Yuan, Wei AU - Figueiredo, Ines AU - Pereira, Rita AU - Ferreira, Ana AU - Riisnaes, Ruth AU - Rodrigues, Daniel Nava AU - Jimenez-Vacas, Juan M AU - Kim, Soojin AU - Uo, Takuma AU - Micco, Patrizio Di AU - Tumber, Anthony AU - Islam, Md Saiful AU - Moesser, Marc A AU - Abboud, Martine AU - Kawamura, Akane AU - Gurel, Bora AU - Christova, Rossitza AU - Gil, Veronica S AU - Buroni, Lorenzo AU - Crespo, Mateus AU - Miranda, Susana AU - Lambros, Maryou B AU - Carreira, Suzanne AU - Tunariu, Nina AU - Alimonti, Andrea AU - Al-Lazikani, Bissan AU - Schofield, Christopher J AU - Plymate, Stephen R AU - Sharp, Adam AU - de Bono, Johann S PY - 2020 DO - 10.1158/0008-5472.CAN-20-1807 UR - http://hdl.handle.net/10668/17533 T2 - Cancer research AB - Endocrine resistance (EnR) in advanced prostate cancer is fatal. EnR can be mediated by androgen receptor (AR) splice variants, with AR splice variant 7 (AR-V7) arguably the most clinically important variant. In this study, we determined proteins key... LA - en PB - American Association for Cancer Research KW - Alternative splicing KW - Antineoplastic agents KW - Cell line, tumor KW - Cohort studies KW - Enzyme inhibitors KW - Gene expression regulation, neoplastic KW - Humans KW - Jumonji domain-containing histone demethylases KW - Male KW - Molecular targeted therapy KW - Oxygenases KW - Prognosis KW - Prostatic neoplasms, castration-resistant KW - Protein isoforms KW - Receptors, androgen KW - Retrospective studies TI - JMJD6 Is a Druggable Oxygenase That Regulates AR-V7 Expression in Prostate Cancer. TY - research article VL - 81 ER -