TY - JOUR AU - Contreras, Cristina AU - Gonzalez-Garcia, Ismael AU - Seoane-Collazo, Patricia AU - Martinez-Sanchez, Noelia AU - Liñares-Pose, Laura AU - Rial-Pensado, Eva AU - Fernø, Johan AU - Tena-Sempere, Manuel AU - Casals, Nuria AU - Dieguez, Carlos AU - Nogueiras, Ruben AU - Lopez, Miguel PY - 2016 DO - 10.2337/db15-1547 UR - http://hdl.handle.net/10668/10448 T2 - Diabetes AB - The chaperone GRP78/BiP (glucose-regulated protein 78 kDa/binding immunoglobulin protein) modulates protein folding in reply to cellular insults that lead to endoplasmic reticulum (ER) stress. This study investigated the role of hypothalamic GRP78 on... LA - en PB - American Diabetes Association KW - Adipose tissue, brown KW - Adipose tissue, white KW - Animals KW - Blotting, Western KW - Diet, high-fat KW - Endoplasmic reticulum stress KW - Fatty acids, nonesterified KW - Hypothalamus KW - Immunohistochemistry KW - Male KW - Obesity KW - Rats KW - Rats, sprague-dawley KW - Real-time polymerase chain reaction KW - Taurochenodeoxycholic acid KW - Temperature KW - Thermogenesis TI - Reduction of Hypothalamic Endoplasmic Reticulum Stress Activates Browning of White Fat and Ameliorates Obesity. TY - research article VL - 66 ER -