TY - JOUR AU - Aouichat, Samira AU - Raya, Enrique AU - Molina-Carballo, Antonio AU - Munoz-Hoyos, Antonio AU - Aloweidi, Abdelkarim Saleh AU - Elmahallawy, Ehab Kotb AU - Agil, Ahmad PY - 2022 DO - 10.3390/antiox11091646 SN - 2076-3921 UR - http://hdl.handle.net/10668/20790 T2 - Antioxidants (Basel, Switzerland) AB - Experimental data have revealed that melatonin at high doses reduced obesity and improved metabolic outcomes in experimental models of obesity, mainly by enhancing brown adipose tissue (BAT) thermogenesis. A potential dose-response relationship has... LA - en PB - MDPI AG KW - BAT KW - UCP1 KW - ZDF rat KW - dose-response KW - melatonin KW - mitochondria KW - obesity KW - thermogenesis KW - Male KW - Rats KW - Animals KW - Melatonin KW - Drinking Water KW - Adipose Tissue, Brown KW - Mitochondrial Dynamics KW - Thermography KW - Obesity KW - Body Weight KW - Diabetes Mellitus KW - Dynamins KW - Fluorescent Antibody Technique KW - Thermogenesis KW - Blotting, Western KW - Models, Theoretical KW - Optic Atrophy KW - Adipocytes TI - Dose-Dependent Effect of Melatonin on BAT Thermogenesis in Zücker Diabetic Fatty Rat: Future Clinical Implications for Obesity. TY - research article VL - 11 ER -