TY - JOUR AU - Quesada, Andrés AU - Vargas, Félix AU - Montoro-Molina, Sebastián AU - O'Valle, Francisco AU - Rodríguez-Martínez, María Dolores AU - Osuna, Antonio AU - Prieto, Isabel AU - Ramírez, Manuel AU - Wangensteen, Rosemary PY - 2012 DO - 10.1371/journal.pone.0040402 UR - http://hdl.handle.net/10668/562 T2 - PloS one AB - This study analyzes the fluorimetric determination of alanyl- (Ala), glutamyl- (Glu), leucyl-cystinyl- (Cys) and aspartyl-aminopeptidase (AspAp) urinary enzymatic activities as early and predictive biomarkers of renal dysfunction in cisplatin-treated... LA - en PB - Public Library of Science KW - Aminopeptidasas KW - Cisplatino KW - Ratas Wistar KW - Marcadores Biológicos KW - Insuficiencia Renal KW - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Peptide Hydrolases::Exopeptidases::Aminopeptidases KW - Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Chlorine Compounds::Cisplatin KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Rats KW - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Biological Markers KW - Medical Subject Headings::Diseases::Male Urogenital Diseases::Urologic Diseases::Kidney Diseases::Renal Insufficiency TI - Urinary aminopeptidase activities as early and predictive biomarkers of renal dysfunction in cisplatin-treated rats TY - research article ER -