RT Journal Article
T1 Transcatheter mitral repair according to the cause of mitral regurgitation: real-life data from the Spanish MitraClip registry.
A1 Pascual, Isaac
A1 Arzamendi, Dabit
A1 Carrasco-Chinchilla, Fernando
A1 Fernández-Vázquez, Felipe
A1 Freixa, Xavier
A1 Nombela-Franco, Luis
A1 Avanzas, Pablo
A1 Serrador Frutos, Ana María
A1 Pan, Manuel
A1 Cid Álvarez, Ana Belén
A1 Hernández-Antolín, Rosa Ana
A1 Andraka Ikazuriaga, Leire
A1 Cruz-González, Ignacio
A1 Díez Gil, José Luis
A1 Alcasena Juango, María Soledad
A1 Berenguer Jofresa, Alberto
A1 Alonso-Briales, Juan H
A1 Li, Chi Hion
A1 Benito González, Tomás
A1 Regueiro, Ander
A1 Armijo, Germán
A1 León, Víctor
A1 Amat-Santos, Ignacio J
A1 Romero, Miguel
A1 Trillo Nouche, Ramiro
A1 Fernández-Golfín, Covadonga
A1 Ruiz Gómez, Lara
A1 Campos-Arjona, Rafael
A1 Millán, Xavier
A1 Garrote Coloma, Carmen
A1 Sanchis, Laura
A1 Jiménez-Quevedo, Pilar
A1 Morís, César
A1 Hernández-García, José María
A1 Serra, Antonio
A1 Pérez de Prado, Armando
A1 Estévez-Loureiro, Rodrigo
K1 Etiology
K1 Etiología
K1 Insuficiencia mitral grave
K1 MitraClip
K1 Reparación de la válvula mitral transcatéter
K1 Severe mitral regurgitation
K1 Transcatheter mitral valve repair
AB Transcatheter mitral valve repair (TMVR) with MitraClip is a therapeutic option for high surgical risk patients with severe mitral regurgitation (MR). The main objective of this study was to analyze differences in outcomes in patients with severe MR according to the cause of MR. Observational, multicenter, and prospective study with consecutive patient inclusion. The primary endpoint was the combination of all-cause mortality and new readmissions due to heart failure after 1 year. We compared clinical and procedural characteristics and the event rate for each MR group. We performed a multivariate analysis to identify predictive variables for the primary endpoint. A total of 558 patients were included: 364 (65.2%) with functional etiology, 111 (19.9%) degenerative and 83 (14.9%) mixed. The mean age was 72.8±11.1 years and 70.3% of the sample were men. There were 95 (17%) events in the overall sample. No significant differences were found in the 3 groups in the number of primary outcome events: 11 (11.3%) in degenerative MR, 71 (21.3%) in functional MR, and 13 (18.1%) in mixed MR (P=.101). Independent predictors were functional class (P=.029), previous surgical revascularization (P=.031), EuroSCORE II (P=.003), diabetes mellitus (P=.037), and left ventricular ejection fraction (P=.015). This study confirms the safety and efficacy of TMVR with MitraClip irrespective of MR etiology in real-life data and shows the main factors related to prognosis during the first year of follow up.
YR 2019
FD 2019-11-13
LK http://hdl.handle.net/10668/14697
UL http://hdl.handle.net/10668/14697
LA en
LA es
DS RISalud
RD Apr 10, 2025