TY - JOUR AU - Llombart-Cussac, Antonio AU - Pérez-García, José Manuel AU - Bellet, Meritxell AU - Dalenc, Florence AU - Gil-Gil, Miguel AU - Ruíz-Borrego, Manuel AU - Gavilá, Joaquín AU - Sampayo-Cordero, Miguel AU - Aguirre, Elena AU - Schmid, Peter AU - Marmé, Frederik AU - Di Cosimo, Serena AU - Gligorov, Joseph AU - Schneeweiss, Andreas AU - Albanell, Joan AU - Zamora, Pilar AU - Wheatley, Duncan AU - Martínez-de Dueñas, Eduardo AU - Amillano, Kepa AU - Malfettone, Andrea AU - Cortés, Javier AU - PARSIFAL Steering Committee and Trial Investigators PY - 2021 DO - 10.1001/jamaoncol.2021.4301 UR - https://hdl.handle.net/10668/27202 T2 - JAMA oncology AB - The cyclin-dependent kinase 4 and 6 inhibitor palbociclib in combination with letrozole has become a standard first-line treatment for patients with endocrine-sensitive, hormone receptor-positive, ERBB2-negative advanced breast cancer. Meanwhile, the... LA - en KW - Antineoplastic Combined Chemotherapy Protocols KW - Breast Neoplasms KW - Female KW - Fulvestrant KW - Humans KW - Letrozole KW - Middle Aged KW - Piperazines KW - Pyridines KW - Receptor, ErbB-2 TI - Fulvestrant-Palbociclib vs Letrozole-Palbociclib as Initial Therapy for Endocrine-Sensitive, Hormone Receptor-Positive, ERBB2-Negative Advanced Breast Cancer: A Randomized Clinical Trial. TY - research article VL - 7 ER -