RT Journal Article
T1 Association of objectively measured physical activity and sedentary time with arterial stiffness in women with systemic lupus erythematosus with mild disease activity.
A1 Morillas-de-Laguno, Pablo
A1 Vargas-Hitos, José A
A1 Rosales-Castillo, Antonio
A1 Sáez-Urán, Luis Manuel
A1 Montalbán-Méndez, Cristina
A1 Gavilán-Carrera, Blanca
A1 Navarro-Mateos, Carmen
A1 Acosta-Manzano, Pedro
A1 Delgado-Fernández, Manuel
A1 Sabio, José M
A1 Ortego-Centeno, Norberto
A1 Callejas-Rubio, José L
A1 Soriano-Maldonado, Alberto
AB To examine the association of objectively measured physical activity (PA) intensity levels and sedentary time with arterial stiffness in women with systemic lupus erythematosus (SLE) with mild disease activity and to analyze whether participants meeting the international PA guidelines have lower arterial stiffness than those not meeting the PA guidelines. The study comprised 47 women with SLE (average age 41.2 [standard deviation 13.9]) years, with clinical and treatment stability during the 6 months prior to the study. PA intensity levels and sedentary time were objectively measured with triaxial accelerometry. Arterial stiffness was assessed through pulse wave velocity, evaluated by Mobil-O-Graph® 24h pulse wave analysis monitor. The average time in moderate to vigorous PA in bouts of ≥10 consecutive minutes was 135.1±151.8 minutes per week. There was no association of PA intensity levels and sedentary time with arterial stiffness, either in crude analyses or after adjusting for potential confounders. Participants who met the international PA guidelines did not show lower pulse wave velocity than those not meeting them (b = -0.169; 95% CI: -0.480 to 0.143; P = 0.280). Our results suggest that PA intensity levels and sedentary time are not associated with arterial stiffness in patients with SLE. Further analyses revealed that patients with SLE meeting international PA guidelines did not present lower arterial stiffness than those not meeting the PA guidelines. Future prospective research is needed to better understand the association of PA and sedentary time with arterial stiffness in patients with SLE.
YR 2018
FD 2018-04-25
LK http://hdl.handle.net/10668/12389
UL http://hdl.handle.net/10668/12389
LA en
DS RISalud
RD Apr 9, 2025