TY - JOUR AU - Fernandez, Agustin F AU - Bayon, Gustavo F AU - Sierra, Marta I AU - Urdinguio, Rocio G AU - ToraƱo, Estela G AU - Garcia, Maria G AU - Carella, Antonella AU - Lopez, Virginia AU - Santamarina, Pablo AU - Perez, Raul F AU - Belmonte, Thalia AU - Tejedor, Juan Ramon AU - Cobo, Isabel AU - Menendez, Pablo AU - Mangas, Cristina AU - Ferrero, Cecilia AU - Rodrigo, Luis AU - Astudillo, Aurora AU - Ortea, Ignacio AU - Cueto Diaz, Sergio AU - Rodriguez-Gonzalez, Pablo AU - Garcia Alonso, J Ignacio AU - Mollejo, Manuela AU - Melendez, Barbara AU - Dominguez, Gemma AU - Bonilla, Felix AU - Fraga, Mario F PY - 2018 DO - 10.1093/hmg/ddy214 UR - http://hdl.handle.net/10668/12561 T2 - Human molecular genetics AB - Aberrant DNA hypermethylation is a hallmark of cancer although the underlying molecular mechanisms are still poorly understood. To study the possible role of 5-hydroxymethylcytosine (5hmC) in this process we analyzed the global and locus-specific... LA - en PB - Oxford University Press KW - 5-Methylcytosine KW - Biomarkers, tumor KW - Case-control studies KW - CpG islands KW - DNA methylation KW - Epigenesis, genetic KW - Gene expression regulation, neoplastic KW - Genome, human KW - Glioma KW - Humans TI - Loss of 5hmC identifies a new type of aberrant DNA hypermethylation in glioma. TY - research article VL - 27 ER -