TY  - JOUR
AU  - Karathanou, Konstantina
AU  - Lazaratos, Michalis
AU  - Bertalan, Éva
AU  - Siemers, Malte
AU  - Buzar, Krzysztof
AU  - Schertler, Gebhard F.X.
AU  - del Val, Coral
AU  - Bondar, Ana-Nicoleta
PY  - 2020
DO  - 10.1016/j.jsb.2020.107617
SN  - 1047-8477
UR  - http://hdl.handle.net/10668/3218
T2  - Journal of Structural Biology
AB  - Corona virus spike protein S is a large homo-trimeric protein anchored in the membrane of the virion particle. Protein S binds to angiotensin-converting-enzyme 2, ACE2, of the host cell, followed by proteolysis of the spike protein, drastic protein...
LA  - en
PB  - Elsevier Inc.
KW  - Bimolecular structure
KW  - Hydrogen bonding
KW  - Dynamic hydrogen-bond clusters
KW  - Conformational plasticity
KW  - SARS-CoV-2 protein S
KW  - ACE2
KW  - Enlace de hidrógeno
KW  - Medical Subject Headings::Information Science::Information Science::Computing Methodologies::Algorithms
KW  - Medical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biology::Computational Biology
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Chemical Processes::Physicochemical Processes::Hydrogen Bonding
KW  - Medical Subject Headings::Information Science::Information Science::Computing Methodologies::Computer Graphics
KW  - Medical Subject Headings::Diseases::Virus Diseases::RNA Virus Infections::Nidovirales Infections::Coronaviridae Infections::Coronavirus Infections
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Models, Theoretical::Models, Molecular
KW  - Medical Subject Headings::Health Care::Environment and Public Health::Public Health::Disease Outbreaks::Epidemics::Pandemics
KW  - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Peptide Hydrolases::Exopeptidases::Dipeptidyl-Peptidases and Tripeptidyl-Peptidases::Peptidyl-Dipeptidase A
KW  - Medical Subject Headings::Diseases::Virus Diseases::Pneumonia, Viral
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Protein Binding
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Molecular Structure::Molecular Conformation::Protein Conformation::Protein Structure, Tertiary::Protein Interaction Domains and Motifs
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Molecular Probe Techniques::Protein Interaction Mapping
KW  - Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Metabolism::Metabolic Networks and Pathways::Protein Interaction Maps
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Molecular Structure::Molecular Conformation::Protein Conformation::Protein Structure, Quaternary
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Molecular Structure::Molecular Conformation::Protein Conformation::Protein Structure, Secondary
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Membrane Fusion Proteins::Viral Fusion Proteins::Spike Glycoprotein, Coronavirus
KW  - Medical Subject Headings::Phenomena and Processes::Microbiological Phenomena::Microbiological Processes::Virus Physiological Processes::Virus Internalization
TI  - A graph-based approach identifies dynamic H-bond communication networks in spike protein S of SARS-CoV-2
TY  - research article
ER  -