RT Journal Article T1 Relative Handgrip Strength as Marker of Cardiometabolic Risk in Women with Systemic Lupus Erythematosus. A1 Sola-Rodríguez, Sergio A1 Vargas-Hitos, José Antonio A1 Gavilán-Carrera, Blanca A1 Rosales-Castillo, Antonio A1 Sabio, José Mario A1 Hernández-Martínez, Alba A1 Martínez-Rosales, Elena A1 Ortego-Centeno, Norberto A1 Soriano-Maldonado, Alberto K1 autoimmune disease K1 body mass index K1 cardiovascular disease K1 cardiovascular risk K1 lupus K1 metabolism K1 muscle strength K1 risk factors AB This study aimed to examine the association of relative handgrip strength (rHGS) with cardiometabolic disease risk factors in women with systemic lupus erythematosus (SLE). Seventy-seven women with SLE (mean age 43.2, SD 13.8) and clinical stability during the previous six months were included. Handgrip strength was assessed with a digital dynamometer and rHGS was defined as absolute handgrip strength (aHGS) divided by body mass index (BMI). We measured blood pressure, markers of lipid and glucose metabolism, inflammation (high sensitivity C-reactive protein [hs-CRP]), arterial stiffness (pulse wave velocity [PWV]), and renal function. A clustered cardiometabolic risk index (z-score) was computed. Pearson's bivariate correlations revealed that higher rHGS was associated with lower systolic blood pressure (SBP), triglycerides, hs-CRP, PWV, and lower clustered cardiometabolic risk (rrange = from -0.43 to -0.23; all p The findings suggest that higher rHGS is significantly associated with lower cardiometabolic risk in women with SLE. YR 2021 FD 2021-04-27 LK http://hdl.handle.net/10668/17724 UL http://hdl.handle.net/10668/17724 LA en DS RISalud RD Apr 17, 2025