RT Journal Article
T1 Feasibility and results of an intensive cardiac rehabilitation program. Insights from the MxM (Más por Menos) randomized trial.
A1 Castro-Conde, Almudena
A1 Abeytua, Manuel
A1 Arrarte Esteban, Vicente I
A1 Caravaca Pérez, Pedro
A1 Dalmau González-Gallarza, Regina
A1 Garza Benito, Fernando
A1 Hidalgo Urbano, Rafael J
A1 Torres Marqués, Joan
A1 Vidal-Pérez, Rafael
A1 Nuñez-Gil, Iván J
K1 Acute coronary syndrome
K1 Calidad de vida
K1 Cardiac rehabilitation
K1 Dieta mediterránea
K1 LDL-cholesterol
K1 Mediterranean diet
K1 Prevención secundaria
K1 Quality of life
K1 Rehabilitación cardiaca
K1 Secondary prevention
K1 Síndrome coronario agudo
K1 cLDL
AB Cardiac rehabilitation programs (CRP) are a set of interventions to improve the prognosis of cardiovascular disease by influencing patients' physical, mental, and social conditions. However, there are no studies evaluating the optimal duration of these programs. We aimed to compare the results of a standard vs a brief intensive CRP in patients after ST-segment elevation and non-ST-segment elevation acute coronary syndrome through the Más por Menos study (More Intensive Cardiac Rehabilitation Programs in Less Time). In this prospective, randomized, open, evaluator-blind for end-point, and multicenter trial (PROBE design), patients were randomly allocated to either standard 8-week CRP or intensive 2-week CRP with booster sessions. A final visit was performed 12 months later, after completion of the program. We assessed adherence to the Mediterranean diet, psychological status, smoking, drug therapy, functional capacity, quality of life, cardiometabolic and anthropometric parameters, cardiovascular events, and all-cause mortality during follow-up. A total of 497 patients (mean age, 57.8±10.0 years; 87.3% men) were finally assessed (intensive: n=262; standard: n=235). Baseline characteristics were similar between the 2 groups. At 12 months, the results of treadmill ergometry improved by ≥ 1 MET in ≥ 93% of the patients. In addition, adherence to the Mediterranean diet and quality of life were significantly improved by CRP, with no significant differences between the groups. The occurrence of cardiovascular events was similar in the 2 groups. Intensive CRP could be as effective as standard CRP in achieving adherence to recommended secondary prevention measures after acute coronary syndrome and could be an alternative for some patients and centers. Registered at ClinicalTrials.gov (Identifier: NCT02619422).
YR 2020
FD 2020-08-15
LK http://hdl.handle.net/10668/16115
UL http://hdl.handle.net/10668/16115
LA en
LA es
DS RISalud
RD Apr 15, 2025