RT Journal Article T1 Association of core body temperature and peripheral blood flow of the hands with pain intensity, pressure pain hypersensitivity, central sensitization, and fibromyalgia symptoms A1 Casas-Barragán, Antonio A1 Molina, Francisco A1 Tapia-Haro, Rosa María A1 García-Ríos, María Carmen A1 Correa-Rodríguez, María A1 Aguilar-Ferrándiz, María Encarnación K1 Central sensitization K1 Core body temperature K1 Fibromyalgia K1 Peripheral nervous system K1 Pain pressure threshold K1 Symptoms K1 Thermography K1 Sensibilización del sistema nervioso central K1 Temperatura corporal K1 Fibromialgia K1 Sistema nervioso periférico K1 Umbral del dolor K1 Signos y síntomas K1 Termografía AB Our aim was to analyse body core temperature and peripheral vascular microcirculation at skin hypothenar eminence of the hands and its relationship to symptoms in fibromyalgia syndrome (FMS). A total of 80 FMS women and 80 healthy women, matched on weight, were enrolled in this case-control study. Thermography and infrared thermometer were used for evaluating the hypothenar regions and core body temperature, respectively. The main outcome measures were pain pressure thresholds (PPTs) and clinical questionnaires. Significant associations were observed between overall impact [β = 0.033; 95% confidence interval (95%CI) = 0.003, 0.062; p = 0.030], daytime dysfunction (β = 0.203; 95%CI = 0.011, 0.395; p = 0.039) and reduced activity (β = 0.045; 95%CI = 0.005, 0.085; p = 0.029) and core body temperature in FMS women. PPTs including greater trochanter dominant (β = 0.254; 95%CI = 0.003, 0.504; p = 0.047), greater trochanter non-dominant (β = 0.650; 95%CI = 0.141, 1.159; p = 0.013), as well as sleeping medication (β = -0.242; 95%CI = -0.471, -0.013; p = 0.039) were also associated with hypothenar eminence temperature. Data highlighted that FMS women showed correlations among body core temperature and hand temperature with the clinical symptoms. PB Sage Publications SN 2040-6223 YR 2021 FD 2021 LK http://hdl.handle.net/10668/4047 UL http://hdl.handle.net/10668/4047 LA en NO Casas-Barragán A, Molina F, Tapia-Haro RM, García-Ríos MC, Correa-Rodríguez M, Aguilar-Ferrándiz ME. Association of core body temperature and peripheral blood flow of the hands with pain intensity, pressure pain hypersensitivity, central sensitization, and fibromyalgia symptoms. Ther Adv Chronic Dis. 2021 Mar 5;12:2040622321997253 DS RISalud RD Apr 6, 2025