TY - JOUR AU - Morales-Ruiz, Teresa AU - Garcia-Ortiz, Maria Victoria AU - Devesa-Guerra, Ivan AU - Raya-Ruiz, Laura AU - Tejedor, Juan R AU - Bayon, Gustavo F AU - Sierra, Marta I AU - Fraga, Mario F AU - Ariza, Rafael R AU - Roldan-Arjona, Teresa PY - 2018 DO - 10.1080/15592294.2017.1414128 UR - http://hdl.handle.net/10668/11902 T2 - Epigenetics AB - Patterns of DNA methylation, an important epigenetic modification involved in gene silencing and development, are disrupted in cancer cells. Understanding the functional significance of aberrant methylation in tumors remains challenging, due in part... LA - en PB - Taylor & Francis KW - DNA demethylation KW - DNA methylation KW - Epigenetics KW - Base excision repair KW - Colon cancer KW - Animals KW - Antineoplastic agents KW - Arabidopsis proteins KW - Cell cycle KW - Cell line, tumor KW - Colonic neoplasms KW - DNA methylation KW - DNA repair KW - Fluorouracil KW - Gene expression regulation, neoplastic KW - Genes, tumor suppressor KW - Genes, p16 KW - Humans KW - Mice, nude KW - N-glycosyl hydrolases KW - Oncogene proteins KW - Oxaliplatin KW - Receptor tyrosine kinase-like orphan receptors KW - Trans-activators KW - Transgenes KW - Xenograft model antitumor assays TI - DNA methylation reprogramming of human cancer cells by expression of a plant 5-methylcytosine DNA glycosylase. TY - research article VL - 13 ER -