RT Journal Article T1 Primary cardiac fibroma in infants: A case report and review of cases of cardiac fibroma managed through orthotopic heart transplant. A1 Rodriguez-Gonzalez, Moises A1 Pérez-Reviriego, Alvaro A A1 Gómez-Guzmán, Elena A1 Tejero-Hernández, María Ángeles A1 Sanz, Alicia Zorrilla A1 Valverde, Israel K1 Cardiac fibroma K1 infants. K1 orthotopic heart transplant AB Cardiac fibromas (CF) are the second most common cardiac tumors in children. They can be aggressive tumors despite their benign histopathologic nature, accounting for the highest mortality rate among primary cardiac tumors. CF usually show a progressive growth and spontaneous regression is rare. Therefore, a complete surgical excision is the preferred therapeutic approach when patients become symptomatic or if mass-related life-threatening complications are anticipated, even in asymptomatic patients. However, some cases are not good candidates for surgical excision due to the impossibility of preserving a normal cardiac anatomy or function after the tumor resection. Orthotopic heart transplantation (OHT) can be an exceptional but adequate alternative for some giant unresectable CF in children. In this article, we report our experience with the case of a 7-month-old infant with a giant unresectable cardiac fibroma who was successfully managed through OHT. SN 0974-2069 YR 2021 FD 2021-04-10 LK https://hdl.handle.net/10668/25944 UL https://hdl.handle.net/10668/25944 LA en DS RISalud RD Apr 5, 2025