RT Journal Article
T1 Testicular germ-cell tumours and penile squamous cell carcinoma: Appropriate management makes the difference.
A1 Nicolai, Nicola
A1 Biasoni, Davide
A1 Catanzaro, Mario A
A1 Colecchia, Maurizio
A1 Trama, Annalisa
K1 Carcinoma
K1 Community network
K1 Europe
K1 Germ cell and embryonal
K1 Neoplasms
K1 Penis neoplasms
K1 Rare diseases
K1 Squamous cell
K1 Survival
K1 Tertiary care centres
K1 Testicular neoplasms
AB Germ-cell tumours (GCT) of the testis and penile squamous cell carcinoma (PeSCC) are a rare and a very rare uro-genital cancers, respectively. Both tumours are well defined entities in terms of management, where specific recommendations - in the form of continuously up-to-dated guide lines-are provided. Impact of these tumour is relevant. Testicular GCT affects young, healthy men at the beginning of their adult life. PeSCC affects older men, but a proportion of these patients are young and the personal consequences of the disease may be devastating. Deviation from recommended management may be a reason of a significant prognostic worsening, as proper treatment favourably impacts on these tumours, dramatically on GCT and significantly on PeSCC. RARECAREnet data may permit to analyse how survivals may vary according to geographical areas, histology and age, leading to assume that non-homogeneous health-care resources may impact the cure and definitive outcomes. In support of this hypothesis, some epidemiologic datasets and clinical findings would indicate that survival may improve when appropriate treatments are delivered, linked to a different accessibility to the best health institutions, as a consequence of geographical, cultural and economic barriers. Finally, strong clues based on epidemiological and clinical data support the hypothesis that treatment delivered at reference centres or under the aegis of a qualified multi-institutional network is associated with a better prognosis of patients with these malignancies. The ERN EURACAN represents the best current European effort to answer this clinical need.
PB Elsevier
YR 2018
FD 2018-02-06
LK http://hdl.handle.net/10668/12229
UL http://hdl.handle.net/10668/12229
LA en
NO Nicolai N, Biasoni D, Catanzaro MA, Colecchia M, Trama A; RARECAREnet Working Group. Testicular germ-cell tumours and penile squamous cell carcinoma: Appropriate management makes the difference. Eur J Surg Oncol. 2019 Jan;45(1):60-66.
DS RISalud
RD Apr 19, 2025