RT Journal Article
T1 Timing of implant-removal in late acute periprosthetic joint infection: A multicenter observational study.
A1 Wouthuyzen-Bakker, Marjan
A1 Sebillotte, Marine
A1 Lomas, Jose
A1 Kendrick, Benjamin
A1 Palomares, Eva Benavent
A1 Murillo, Oscar
A1 Parvizi, Javad
A1 Shohat, Noam
A1 Reinoso, Javier Cobo
A1 Sánchez, Rosa Escudero
A1 Fernandez-Sampedro, Marta
A1 Senneville, Eric
A1 Huotari, Kaisa
A1 Allende, José Maria Barbero
A1 García, Antonio Blanco
A1 Lora-Tamayo, Jaime
A1 Ferrari, Matteo Carlo
A1 Vaznaisiene, Danguole
A1 Yusuf, Erlangga
A1 Aboltins, Craig
A1 Trebse, Rihard
A1 Salles, Mauro José
A1 Benito, Natividad
A1 Vila, Andrea
A1 Toro, Maria Dolores Del
A1 Kramer, Tobias Siegfried
A1 Petersdorf, Sabine
A1 Diaz-Brito, Vicens
A1 Tufan, Zeliha Kocak
A1 Sanchez, Marisa
A1 Arvieux, Cédric
A1 Soriano, Alex
A1 ESCMID Study Group for Implant-Associated Infections (ESGIAI), 
K1 Debridement
K1 Failure
K1 Hematogenous
K1 Late acute
K1 Periprosthetic joint infection
K1 Revision surgery
AB We evaluated the treatment outcome in late acute (LA) periprosthetic joint infections (PJI) treated with debridement and implant retention (DAIR) versus implant removal. In a large multicenter study, LA PJIs of the hip and knee were retrospectively evaluated. Failure was defined as: PJI related death, prosthesis removal or the need for suppressive antibiotic therapy. LA PJI was defined as acute symptoms  445 patients were included, comprising 340 cases treated with DAIR and 105 cases treated with implant removal (19% one-stage revision (n = 20), 74.3% two-stage revision (n = 78) and 6.7% definitive implant removal (n = 7). Overall failure in patients treated with DAIR was 45.0% (153/340) compared to 24.8% (26/105) for implant removal (p  DAIR is a viable surgical treatment for most patients with LA PJI, but implant removal should be considered in a subset of patients, especially in those with a CRIME80-score ≥3.
YR 2019
FD 2019-07-15
LK http://hdl.handle.net/10668/14254
UL http://hdl.handle.net/10668/14254
LA en
DS RISalud
RD Apr 20, 2025