RT Journal Article
T1 Probiotics Dietary Supplementation for Modulating Endocrine and Fertility Microbiota Dysbiosis
A1 López-Moreno, Ana
A1 Aguilera, Margarita
K1 Probiotics
K1 Doses
K1 Microbiota
K1 Endocrine
K1 Fertility
K1 Dysbiosis
K1 Probióticos
K1 Dosificación
K1 Sistema endocrino
K1 Fertilidad
K1 Disbiosis
AB Human microbiota seems to play a key role in endocrine and reproductive systems. Fortunately, microbiota reproductive dysbiosis start to be treated by probiotics using typical species from genus Lactobacillus. This work presents the compiled and analysed results from the most up-to-date information from clinical trials regarding microbiota, fertility, probiotics and oral route administration, reviewing open access scientific documents. These studies analyse the clinical impact of probiotics administered on several endocrine disorders’ manifestations in women: mastitis; vaginal dysbiosis; pregnancy complication disorders; and polycystic ovary syndrome. In all cases, the clinical modulation achieved by probiotics was evaluated positively through the improvement of specific disease outcomes with the exception of the pregnancy disorders studies, where the sample sizes results were statistically insufficient. High amounts of studies were discarded because no data were provided on specific probiotic strains, doses, impact on the individual autochthon microbiota, or data regarding specific hormonal values modifications and endocrine regulation effects. However, most of the selected studies with probiotics contained no protocolised administration. Therefore, we consider that intervention studies with probiotics might allocate the focus, not only in obtaining a final outcome, but in how to personalise the administration according to the disorder to be palliated.
PB MDPI
YR 2020
FD 2020-03-13
LK http://hdl.handle.net/10668/3596
UL http://hdl.handle.net/10668/3596
LA en
NO López-Moreno A, Aguilera M. Probiotics Dietary Supplementation for Modulating Endocrine and Fertility Microbiota Dysbiosis. Nutrients. 2020 Mar 13;12(3):757
DS RISalud
RD Apr 6, 2025