%0 Journal Article
%A Meseguer Barros, Carmen Marina
%A Alzueta Isturiz, Natalia
%A Sainz de Rozas Aparicio, Rita
%A Vizcaíno, Rafael Aguilella
%A López Esteban, Laura
%A Anaya Ordóñez, Sonia
%A Lekue Alkorta, Itxasne
%A Martín Suances, Salvadora
%A Jiménez Arce, Jorge Ignacio
%A Fernández Vicente, Maite
%A Borrego Izquierdo, Yolanda
%A Prieto Sánchez, Raquel
%A Casado Casuso, Silvia
%A Madridejos, Rosa
%A Verde, Carmen Marquina
%A Tomás Sanz, Rosa
%A Oro Fernández, María
%A Gallardo Borge, Sara
%A Lázaro López, Eva
%A Pina Gadea, María Belén
%A Pereira Pía, Mercedes
%A Maestre-Sánchez, María Victoria
%A Ribes-Murillo, Esther
%A Gómez de Oña, Constanza
%A María Jesús Lallana, Álvarez
%A Celaya Lecea, Concepción
%A Prado Prieto, María Ana
%A Aranguez Ruiz, Aranzazu
%A Olmo Quintana, Vicente
%A Villén Romero, Noemí
%A Payá Giner, Carolina
%A Lloret Callejo, Angeles
%A Fernández Ferreiro, Alvaro
%A Basagoiti Carreño, Blanca
%A Iglesias Iglesias, Ana Aurelia
%A Martín Alonso, Antonio
%A Díez Alcántara, Ana
%A Marco Tejón, Esther
%A Lestón Vázquez, Marta
%A Ariza Copado, Mª Ángeles
%A Aparicio Cueva, Marta
%A Escudero Vilaplana, Belén
%A Nicieza, Marisa
%A Picazo Sanchiz, Gracia
%A Silva Riádigos, Genma María
%A Sánchez, Lucía Jamart
%A García Álvarez, Ángel
%A García Bonilla, Antonio
%A Herrero Delicado, Rafael
%A Arroyo Pineda, Virginia
%A de la Hija, Belén
%A Troncoso Mariño, Amelia
%A Tofiño González, Isabel
%A Mateu García, Mónica Susana
%A García Vázquez, Pablo
%A Pérez Martín, Joaquín
%A Fernández-Urrusuno, Rocío
%T Sars-Cov-2 Infection in Patients on Long-Term Treatment with Macrolides in Spain: A National Cross-Sectional Study.
%D 2021
%@ 2079-6382
%U https://hdl.handle.net/10668/24734
%X The aim of this study was to know the prevalence and severity of COVID-19 in patients treated with long-term macrolides and to describe the factors associated with worse outcomes. A cross-sectional study was conducted in Primary Care setting. Patients with macrolides dispensed continuously from 1 October 2019 to 31 March 2020, were considered. Main outcome: diagnosis of coronavirus disease-19 (COVID-19). Secondary outcomes: symptoms, severity, characteristics of patients, comorbidities, concomitant treatments. A total of 3057 patients met the inclusion criteria. Median age: 73 (64-81) years; 55% were men; 62% smokers/ex-smokers; 56% obese/overweight. Overall, 95% of patients had chronic respiratory diseases and four comorbidities as a median. Prevalence of COVID-19: 4.8%. This was in accordance with official data during the first wave of the pandemic. The most common symptoms were respiratory: shortness of breath, cough, and pneumonia. Additionally, 53% percent of patients had mild/moderate symptoms, 28% required hospital admission, and 19% died with COVID-19. The percentage of patients hospitalized and deaths were 2.6 and 5.8 times higher, respectively, in the COVID-19 group (p
%K COVID-19
%K SARS-CoV-2
%K ambulatory care
%K azithromycin
%K long-term treatment
%K macrolides
%K outpatients
%~