%0 Journal Article %A Álvarez-Zaballos, Sara %A González-Ramallo, Victor %A Quintana, Eduard %A Muñoz, Patricia %A de la Villa-Martínez, Sofía %A Fariñas, M Carmen %A Arnáiz-de Las Revillas, Francisco %A de Alarcón, Arístides %A Rodríguez-Esteban, M Ángeles %A Miró, José M %A Goenaga, Miguel Angel %A Goikoetxea-Agirre, Josune %A García-Vázquez, Elisa %A Boix-Palop, Lucía %A Martínez-Sellés, Manuel %A On Behalf Of Games, %T Multivalvular Endocarditis: A Rare Condition with Poor Prognosis. %D 2022 %@ 2077-0383 %U http://hdl.handle.net/10668/21333 %X Background. Infective endocarditis (IE) is a severe condition. Our aim was to describe the profile and prognosis of patients with multivalvular infective endocarditis (MIE) and compare them to single-valve IE (SIE). Methods. We used a retrospective analysis of the Spanish IE Registry (2008−2020). Results. From 4064 definite cases of valvular IE, 577 (14.2%) had MIE. In patients with MIE, the most common locations were mitral (552, 95.7%) and aortic (550, 95.3%), with mitral-aortic involvement present in 507 patients (87.9%). The most common etiologies were S. viridans (192, 33.3%) and S. aureus (113, 19.6%). MIE involved only native valves in 450 patients (78.0%). Compared with patients with SIE, patients with MIE had a similar age (69 vs. 67 years, respectively, p = 0.27) and similar baseline characteristics, but were more frequently men (67.1% vs. 72.9%, p = 0.005) and had a higher incidence of intracardiac complications (36.2% vs. 50.4%, p %K infective endocarditis %K mortality %K multivalvular endocarditis %K prognosis %~