TY  - JOUR
AU  - González-Guerra, José Luis
AU  - Castilla-Cortazar, Inma
AU  - Aguirre, Gabriel A
AU  - Muñoz, Úrsula
AU  - Martín-Estal, Irene
AU  - Ávila-Gallego, Elena
AU  - Granado, Miriam
AU  - Puche, Juan E
AU  - García-Villalón, Ángel Luis
PY  - 2017
DO  - 10.1371/journal.pone.0181760
UR  - http://hdl.handle.net/10668/11498
T2  - PloS one
AB  - Circulating levels of IGF-1 may decrease under several circumstances like ageing, metabolic syndrome, and advanced cirrhosis. This reduction is associated with insulin resistance, dyslipidemia, progression to type 2 diabetes, and increased risk for...
LA  - en
KW  - Angiotensin II
KW  - Animals
KW  - Body Weight
KW  - Bradykinin
KW  - Extracellular Matrix
KW  - Gene Expression Regulation
KW  - Hemodynamics
KW  - Insulin-Like Growth Factor I
KW  - Mice, Transgenic
KW  - Myocardial Contraction
KW  - Myocardium
KW  - Organ Size
KW  - Perfusion
KW  - Real-Time Polymerase Chain Reaction
KW  - Vasoconstriction
KW  - Vasodilation
TI  - Partial IGF-1 deficiency is sufficient to reduce heart contractibility, angiotensin II sensibility, and alter gene expression of structural and functional cardiac proteins.
TY  - research article
VL  - 12
ER  -