TY  - JOUR
AU  - Kared, Hassen
AU  - Tan, Shu Wen
AU  - Lau, Mai Chan
AU  - Chevrier, Marion
AU  - Tan, Crystal
AU  - How, Wilson
AU  - Wong, Glenn
AU  - Strickland, Marie
AU  - Malleret, Benoit
AU  - Amoah, Amanda
AU  - Pilipow, Karolina
AU  - Zanon, Veronica
AU  - Govern, Naomi Mc
AU  - Lum, Josephine
AU  - Chen, Jin Miao
AU  - Lee, Bernett
AU  - Florian, Maria Carolina
AU  - Geiger, Hartmut
AU  - Ginhoux, Florent
AU  - Ruiz-Mateos, Ezequiel
AU  - Fulop, Tamas
AU  - Rajasuriar, Reena
AU  - Kamarulzaman, Adeeba
AU  - Ng, Tze Pin
AU  - Lugli, Enrico
AU  - Larbi, Anis
PY  - 2020
DO  - 10.1038/s41467-020-14442-6
UR  - http://hdl.handle.net/10668/3859
T2  - Nature Communications
AB  - The diversity of the naïve T cell repertoire drives the replenishment potential and capacity of memory T cells to respond to immune challenges. Attrition of the immune system is associated with an increased prevalence of pathologies in aged...
LA  - en
PB  - Springer Nature
KW  - Memory T cells
KW  - Wnt signaling pathway
KW  - Flow cytometry
KW  - Immune system
KW  - Catenins
KW  - Células T de memoria
KW  - Vía de señalización wnt
KW  - Citometría de flujo
KW  - Sistema inmunológico
KW  - Cateninas
KW  - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Physiological Processes::Growth and Development::Aging
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals
KW  - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Antigens
KW  - Medical Subject Headings::Anatomy::Hemic and Immune Systems::Immune System::Leukocytes::Leukocytes, Mononuclear::Lymphocytes::T-Lymphocytes::CD4-Positive T-Lymphocytes
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Gene Expression Profiling
KW  - Medical Subject Headings::Diseases::Immune System Diseases::Immunologic Deficiency Syndromes::HIV Infections
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Phenomena and Processes::Immune System Phenomena::Immunity::Adaptive Immunity::Immunologic Memory
KW  - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Intercellular Signaling Peptides and Proteins
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice
KW  - Medical Subject Headings::Anatomy::Cells::Stem Cells::Hematopoietic Stem Cells::Lymphoid Progenitor Cells::Precursor Cells, T-Lymphoid
KW  - Medical Subject Headings::Anatomy::Tissues::Lymphoid Tissue::Thymus Gland
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Chemical Processes::Biochemical Processes::Signal Transduction::Wnt Signaling Pathway
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Transcription Factors::beta Catenin
TI  - Immunological history governs human stem cell memory CD4 heterogeneity via the Wnt signaling pathway
TY  - research article
ER  -