RT Journal Article T1 Assessment of the Phytochemical and Nutrimental Composition of Dark Chia Seed (Salvia hispánica L.) A1 Rodríguez Lara, Avilene A1 Mesa-García, María Dolores A1 Medina, Karla Alejandra Damián A1 Quirantes Piné, Rosa A1 Casuso, Rafael A. A1 Segura Carretero, Antonio A1 Huertas, Jesús Rodríguez K1 Chia seed K1 Functional food K1 Fiber K1 Omega-3 K1 Polyunsaturated fatty acids K1 Essential amino acids K1 Nucleosides K1 Phenolic compounds K1 Semillas K1 Salvia hispanica K1 Alimentos funcionales K1 Fibras de la dieta K1 Ácidos grasos Omega-3 K1 Ácidos grasos insaturados K1 Aminoácidos esenciales K1 Nucleósidos K1 Compuestos fenólicos AB Chia seeds are rich sources of different macro and micronutrients associated with health benefits; thus, they may be considered as a functional food. However, the composition depends on the variety, origin, climate and soil. Here, we show a comprehensive characterization of extractable and non-extractable phenolic compounds of dark chia seed Salvia hispanica L. using high-performance liquid chromatography-electrospray ionization-quadrupole time-of-flight (HPLC-ESI-QTOF) and discuss potential health benefits associated with the presence of a number of nutritional and bioactive compounds. We report that dark chia from Jalisco is a high-fiber food, containing omega-3 polyunsaturated fatty acids, essential amino acids (phenylalanine and tryptophan), and nucleosides (adenosine, guanidine and uridine), and rich in antioxidant phenolic compounds, mainly caffeic acid metabolites. Our data suggest that chia seeds may be used as ingredients for the development of functional foods and dietary supplements. PB MDPI YR 2021 FD 2021-12-04 LK http://hdl.handle.net/10668/4566 UL http://hdl.handle.net/10668/4566 LA en NO Rodríguez Lara A, Mesa-García MD, Medina KAD, Quirantes Piné R, Casuso RA, Segura Carretero A, et al. Assessment of the Phytochemical and Nutrimental Composition of Dark Chia Seed (Salvia hispánica L.). Foods. 2021 Dec 4;10(12):3001 DS RISalud RD Apr 19, 2025