TY - JOUR AU - Plaisance, Valerie AU - Brajkovic, Saska AU - Tenenbaum, Mathie AU - Favre, Dimitri AU - Ezanno, Helene AU - Bonnefond, Amelie AU - Bonner, Caroline AU - Gmyr, Valery AU - Kerr-Conte, Julie AU - Gauthier, Benoit R. AU - Widmann, Christian AU - Waeber, Gerard AU - Pattou, Francois AU - Froguel, Philippe AU - Abderrahmani, Amar PY - 2016 DO - 10.1371/journal.pone.0163046 SN - 1932-6203 UR - http://hdl.handle.net/10668/19161 T2 - Plos one AB - Elevated plasma concentration of the pro-atherogenic oxidized low density lipoprotein cholesterol (LDL) triggers adverse effects in pancreatic beta-cells and is associated with type 2 diabetes. Here, we investigated whether the endoplasmic reticulum... LA - en PB - Public library science KW - Unfolded protein response KW - Diabetes-mellitus KW - Density-lipoproteins KW - Er stress KW - Macrophages KW - Apoptosis KW - Antioxidants KW - Metabolism KW - Activation KW - Expression TI - Endoplasmic Reticulum Stress Links Oxidative Stress to Impaired Pancreatic Beta-Cell Function Caused by Human Oxidized LDL TY - research article VL - 11 ER -