RT Journal Article T1 SEOM clinical guideline of diagnosis and management of low-grade glioma (2017). A1 Sepulveda-Sanchez, J M A1 Muñoz-Langa, J A1 Arraez, M A A1 Fuster, J A1 Hernandez Lain, A A1 Reynes, G A1 Rodriguez-Gonzalez, V A1 Vicente, E A1 Vidal-Denis, M A1 Gallego, O K1 Astrocytoma K1 Guideline K1 Low-grade glioma K1 Neurooncology K1 Oligodendroglioma AB Diffuse infiltrating low-grade gliomas include oligodendrogliomas and astrocytomas, and account for about 5% of all primary brain tumors. Treatment strategies for these low-grade gliomas in adults have recently changed. The 2016 World Health Organization (WHO) classification has updated the definition of these tumors to include their molecular characterization, including the presence of isocitrate dehydrogenase (IDH) mutation and 1p/19p codeletion. In this new classification, the histologic subtype of grade II-mixed oligoastrocytoma has also been eliminated. The precise optimal management of patients with low-grade glioma after resection remains to be determined. The risk-benefit ratio of adjuvant treatment must be weighed for each individual. PB Springer YR 2017 FD 2017-11-09 LK http://hdl.handle.net/10668/11787 UL http://hdl.handle.net/10668/11787 LA en NO Sepúlveda-Sánchez JM, Muñoz Langa J, Arráez MÁ, Fuster J, Hernández Laín A, Reynés G, et al. SEOM clinical guideline of diagnosis and management of low-grade glioma (2017). Clin Transl Oncol. 2018 Jan;20(1):3-15 DS RISalud RD Apr 18, 2025