TY  - JOUR
AU  - Gómez-Herreros, Fernando
AU  - Zagnoli-Vieira, Guido
AU  - Ntai, Ioanna
AU  - Martínez-Macías, María Isabel
AU  - Anderson, Rhona M
AU  - Herrero-Ruíz, Andrés
AU  - Caldecott, Keith W
PY  - 2017
DO  - 10.1038/s41467-017-00307-y
UR  - http://hdl.handle.net/10668/11493
T2  - Nature communications
AB  - DNA double-strand breaks (DSBs) induced by abortive topoisomerase II (TOP2) activity are a potential source of genome instability and chromosome translocation. TOP2-induced DNA double-strand breaks are rejoined in part by tyrosyl-DNA phosphodiesterase...
LA  - en
KW  - DNA Breaks, Double-Stranded
KW  - DNA End-Joining Repair
KW  - DNA Repair
KW  - DNA Topoisomerases, Type II
KW  - DNA-Binding Proteins
KW  - Humans
KW  - Nuclear Proteins
KW  - Phosphoric Diester Hydrolases
KW  - Poly-ADP-Ribose Binding Proteins
KW  - Transcription Factors
KW  - Transcription, Genetic
KW  - Translocation, Genetic
TI  - TDP2 suppresses chromosomal translocations induced by DNA topoisomerase II during gene transcription.
TY  - research article
VL  - 8
ER  -