RT Journal Article
T1 Prolonged Mechanical Ventilation as a Predictor of Mortality After Cardiac Surgery.
A1 Fernandez-Zamora, Maria Dolores
A1 Gordillo-Brenes, Antonio
A1 Banderas-Bravo, Esther
A1 Arboleda-Sánchez, José Andrés
A1 Hinojosa-Pérez, Rafael
A1 Aguilar-Alonso, Eduardo
A1 Herruzo-Aviles, Ángel
A1 Curiel-Balsera, Emilio
A1 Sánchez-Rodríguez, Ángel
A1 Rivera-Fernández, Ricardo
A1 ARIAM Andalucía Group, 
K1 cardiac surgery
K1 mechanical ventilation
K1 mortality
K1 severity
AB Mortality among the small percentage of cardiac surgery patients receiving prolonged mechanical ventilation is high, but this issue appears to be inadequately addressed in guidelines. This study is a retrospective analysis of prospective, multi-center, and observational study in Spain including all adults undergoing cardiac surgery in 3 Andalusian hospitals between June 2008 and December 2012. The study included 3,588 adults with mean ± SD age of 63.5 ± 12.8 y and with median (interquartile range) EuroSCORE of 5 (3-7) points. Prolonged mechanical ventilation (> 24 h) was required by 415 subjects (11.6%), with ICU mortality of 44.3% (184 subjects), and was not required by 3,173 subjects (88.4%), with ICU mortality of 3.1% (99 subjects, P  24 h) was required by 415 subjects (11.6%), with ICU mortality of 44.3% (184 subjects), and was not required by 3,173 subjects (88.4%), with ICU mortality of 3.1% (99 subjects, P  10. In the multivariable analysis, ICU mortality was associated with illness severity, duration of bypass surgery, surgery type, and prolonged mechanical ventilation (odds ratio 15.19, 95% CI 11.56-22.09). The main cause of death was multiple organ failure and sepsis in subjects who required prolonged mechanical ventilation (50.3%) and cardiogenic shock in those who did not (59.2%). Prolonged postoperative mechanical ventilation was required by 10-20% of cardiac surgery subjects, who constitute a specific group that represents most of the postoperative mortality, which is associated with multiple organ failure and sepsis.
YR 2018
FD 2018-01-30
LK http://hdl.handle.net/10668/12064
UL http://hdl.handle.net/10668/12064
LA en
DS RISalud
RD Apr 8, 2025