%0 Journal Article
%A Fernandez-Zamora, Maria Dolores
%A Gordillo-Brenes, Antonio
%A Banderas-Bravo, Esther
%A Arboleda-Sánchez, José Andrés
%A Hinojosa-Pérez, Rafael
%A Aguilar-Alonso, Eduardo
%A Herruzo-Aviles, Ángel
%A Curiel-Balsera, Emilio
%A Sánchez-Rodríguez, Ángel
%A Rivera-Fernández, Ricardo
%A ARIAM Andalucía Group
%T Prolonged Mechanical Ventilation as a Predictor of Mortality After Cardiac Surgery.
%D 2018
%U http://hdl.handle.net/10668/12064
%X Mortality among the small percentage of cardiac surgery patients receiving prolonged mechanical ventilation is high, but this issue appears to be inadequately addressed in guidelines. This study is a retrospective analysis of prospective, multi-center, and observational study in Spain including all adults undergoing cardiac surgery in 3 Andalusian hospitals between June 2008 and December 2012. The study included 3,588 adults with mean ± SD age of 63.5 ± 12.8 y and with median (interquartile range) EuroSCORE of 5 (3-7) points. Prolonged mechanical ventilation (> 24 h) was required by 415 subjects (11.6%), with ICU mortality of 44.3% (184 subjects), and was not required by 3,173 subjects (88.4%), with ICU mortality of 3.1% (99 subjects, P  24 h) was required by 415 subjects (11.6%), with ICU mortality of 44.3% (184 subjects), and was not required by 3,173 subjects (88.4%), with ICU mortality of 3.1% (99 subjects, P  10. In the multivariable analysis, ICU mortality was associated with illness severity, duration of bypass surgery, surgery type, and prolonged mechanical ventilation (odds ratio 15.19, 95% CI 11.56-22.09). The main cause of death was multiple organ failure and sepsis in subjects who required prolonged mechanical ventilation (50.3%) and cardiogenic shock in those who did not (59.2%). Prolonged postoperative mechanical ventilation was required by 10-20% of cardiac surgery subjects, who constitute a specific group that represents most of the postoperative mortality, which is associated with multiple organ failure and sepsis.
%K cardiac surgery
%K mechanical ventilation
%K mortality
%K severity
%~