RT Journal Article T1 Genetics and molecular epidemiology of multiple myeloma: the rationale for the IMMEnSE consortium (review). A1 Martino, Alessandro A1 Sainz, Juan A1 Buda, Gabriele A1 Jamroziak, Krzysztof A1 Reis, Rui Manuel A1 García-Sanz, Ramón A1 Jurado, Manuel A1 Ríos, Rafael A1 Szemraj-Rogucka, Zofia A1 Marques, Herlander A1 Lesueur, Fabienne A1 Moreno, Victor A1 Orciuolo, Enrico A1 Gemignani, Federica A1 Landi, Stefano A1 Rossi, Anna Maria A1 Dumontet, Charles A1 Petrini, Mario A1 Campa, Daniele A1 Canzian, Federico K1 IMMEnSE consortium, K1 Multiple myeloma K1 SNPs K1 Genetic susceptibility K1 Hharmacogenetics K1 Humanos K1 Variación Genética K1 Farmacogenética K1 Factores de Riesg0 K1 Mieloma Múltiple K1 Epidemiología Molecular AB There is strong evidence suggesting the presence of a genetic component in the aetiology of multiple myeloma (MM). However no genetic risk factors have been unequivocally established so far. To further our understanding of the genetic determinants of MM risk, a promising strategy is to collect a large set of patients in a consortium, as successfully done for other cancers. In this article, we review the main findings in the genetic susceptibility and pharmacogenetics of MM and present the strategy of the IMMEnSE (International Multiple Myeloma rESEarch) consortium in contributing to determine the role of genetic variation in pharmacogenetics and in MM risk. PB Spandidos Publications SN 1019-6439 YR 2012 FD 2012-03 LK http://hdl.handle.net/10668/1379 UL http://hdl.handle.net/10668/1379 LA en NO Martino A, Sainz J, Buda G, Jamroziak K, Reis RM, García-Sanz R, et al. Genetics and molecular epidemiology of multiple myeloma: the rationale for the IMMEnSE consortium (review). Int. J. Oncol. 2012; 40(3):625-38 NO Journal Article; Research Support, Non-U.S. Gov't; Review; DS RISalud RD Apr 19, 2025