%0 Journal Article
%A Barnadas, A
%A Muñoz, M
%A Margelí, M
%A Chacón, J I
%A Cassinello, J
%A Antolin, S
%A Adrover, E
%A Ramos, M
%A Carrasco, E
%A Jimeno, M A
%A Ojeda, B
%A González, X
%A González, S
%A Constenla, M
%A Florián, J
%A Miguel, A
%A Llombart, A
%A Lluch, A
%A Ruiz-Borrego, M
%A Colomer, R
%A Del Barco, S
%A GEICAM, Spanish Breast Cancer Group
%T BOMET-QoL-10 questionnaire for breast cancer patients with bone metastasis: the prospective MABOMET GEICAM study.
%D 2019
%U https://hdl.handle.net/10668/25668
%X Bone metastasis (BM) is the most common site of disease in metastatic breast cancer (MBC) patients. BM impacts health-related quality of life (HRQoL). We tested prospectively the psychometric properties of the Bone Metastasis Quality of Life (BOMET-QoL-10) measure on MBC patients with BM. Patients completed the BOMET-QoL-10 questionnaire, the Visual Analogue Scale (VAS) for pain, and a self-perceived health status item at baseline and at follow-up visits. We performed psychometric tests and calculated the effect size of specific BM treatment on patients´ HRQoL. Almost 70% of the 172 patients reported symptoms, 23.3% experienced irruptive pain, and over half were receiving chemotherapy. BOMET-QoL-10 proved to be a quick assessment tool performing well in readability and completion time (about 10 min) with 0-1.2% of missing/invalid data. Although BOMET-QoL-10 scores remained fairly stable during study visits, differences were observed for patient subgroups (e.g., with or without skeletal-related events or adverse effects). Scores were significantly correlated with physician-reported patient status, patient-reported pain, symptoms, and perceived health status. BOMET-QoL-10 scores also varied prospectively according to changes in pain intensity. BOMET-QoL-10 performed well as a brief, easy-to-administer, useful, and sensitive HRQoL measure for potential use for clinical practice with MBC patients. NCT03847220. Retrospectively registered on clinicaltrials.gov (February the 20th 2019).
%K Assessments
%K Bone metastasis
%K Metastatic breast cancer
%K Psychometric
%K Quality of life
%K Treatment
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