TY - JOUR AU - Ortega-Sáenz, Patricia AU - Moreno-Domínguez, Alejandro AU - Gao, Lin AU - López-Barneo, José PY - 2020 DO - 10.3389/fphys.2020.614893 UR - http://hdl.handle.net/10668/3708 T2 - Frontiers in Physiology AB - Carotid body glomus cells are multimodal arterial chemoreceptors able to sense and integrate changes in several physical and chemical parameters in the blood. These cells are also essential for O2 homeostasis. Glomus cells are prototypical peripheral... LA - en PB - Frontiers KW - Carotid body KW - Glomus cells KW - Acute O2 sensing KW - Electron transport chain KW - Mitochondrial signaling KW - Ion channels KW - Mechanism of disease KW - Paraganglioma KW - Cuerpo carotídeo KW - Enfermedades mitocondriales KW - Mitocondrias KW - Canales iónicos KW - Medical Subject Headings::Anatomy::Nervous System::Neurons::Neurons, Afferent::Sensory Receptor Cells::Chemoreceptor Cells::Paraganglia, Nonchromaffin::Carotid Body KW - Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Mitochondrial Diseases KW - Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Mitochondria KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Carrier Proteins::Membrane Transport Proteins::Ion Channels KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice KW - Medical Subject Headings::Organisms::Eukaryota::Animals KW - Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Oxygen Compounds::Reactive Oxygen Species KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Respiration::Cell Hypoxia KW - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Physiological Processes::Homeostasis KW - Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Metabolism::Oxidative Stress TI - Molecular Mechanisms of Acute Oxygen Sensing by Arterial Chemoreceptor Cells. Role of Hif2α TY - review article ER -