TY - JOUR AU - Van De Sande, Michiel AU - Tap, William D AU - Gelhorn, Heather L AU - Ye, Xin AU - Speck, Rebecca M AU - Palmerini, Emanuela AU - Stacchiotti, Silvia AU - Desai, Jayesh AU - Wagner, Andrew J AU - Alcindor, Thierry AU - Ganjoo, Kristen AU - Martín-Broto, Javier AU - Wang, Qiang AU - Shuster, Dale AU - Gelderblom, Hans AU - Healey, John H PY - 2021 DO - 10.1080/17453674.2021.1922161 UR - http://hdl.handle.net/10668/17780 T2 - Acta orthopaedica AB - Background and purpose - The ENLIVEN trial showed that, after 25 weeks, pexidartinib statistically significantly reduced tumor size more than placebo in patients with symptomatic, advanced tenosynovial giant cell tumor (TGCT) for whom surgery was not... LA - en KW - Adult KW - Aminopyridines KW - Double-Blind Method KW - Female KW - Giant Cell Tumor of Tendon Sheath KW - Humans KW - Lower Extremity KW - Male KW - Middle Aged KW - Patient Reported Outcome Measures KW - Pyrroles TI - Pexidartinib improves physical functioning and stiffness in patients with tenosynovial giant cell tumor: results from the ENLIVEN randomized clinical trial. TY - research article VL - 92 ER -