TY  - JOUR
AU  - Turnbull, Alice
AU  - Bermejo-Rodríguez, Camino
AU  - Preston, Mark A
AU  - Garrido-Barros, María
AU  - Pimentel, Belén
AU  - de la Cueva-Méndez, Guillermo
PY  - 2019
DO  - 10.1021/acssynbio.9b00172
UR  - http://hdl.handle.net/10668/14311
T2  - ACS synthetic biology
AB  - Although not evolved to function in eukaryotes, prokaryotic toxin Kid induces apoptosis in human cells, and this is avoided by coexpression of its neutralizing antitoxin, Kis. Inspired by the way Kid becomes active in bacterial cells we had previously...
LA  - en
KW  - Kid-Kis
KW  - cancer cell killing
KW  - gene therapy
KW  - miR373
KW  - onco-miRNA
KW  - toxin−antitoxin
KW  - Apoptosis
KW  - Bacterial Proteins
KW  - Bacterial Toxins
KW  - Blotting, Western
KW  - Cell Death
KW  - Cell Line
KW  - Cell Proliferation
KW  - Doxycycline
KW  - Gene Expression Regulation, Bacterial
KW  - HEK293 Cells
KW  - Humans
KW  - MicroRNAs
KW  - Toxin-Antitoxin Systems
TI  - Targeted Cancer Cell Killing by Highly Selective miRNA-Triggered Activation of a Prokaryotic Toxin-Antitoxin System.
TY  - research article
VL  - 8
ER  -