RT Journal Article
T1 Skin-colored papules on the cheeks, acrochordons on the axillae.
A1 Lopez-Riquelme, Irene
A1 Ayala-Blanca, Maria
A1 Gomez-Moyano, Elisabeth
K1 Skin Neoplasms
K1 Skin Abnormalities
K1 Mutation
K1 Genetic Testing
AB A 43-year-old woman presented to the dermatology department with multiple small skin-colored papules on her cheeks (Figure 1) and acrochordons (“skin tags”) on the axillae (Figure 2). She reported that they had appeared over the past few years. Her personal medical history was unremarkable, but she had a fi rst-degree relative with renal carcinoma. Biopsy of a papule revealed dermal follicular structures surrounded by a perifollicular fi brous sheath and a densely fi brous stroma, consistent with a fi brofolliculoma (Figure 3), ie, a benign hair follicle tumor pathognomonic for Birt-HoggDubé (BHD) syndrome. Subsequent genetic testing found a mutation in the FLCN gene, confi rming the diagnosis. Computed tomography showed no evidence of lung cysts or kidney tumor. Regular cancer surveillance was instituted.
PB Cleveland Clinic Educational Foundation
YR 2022
FD 2022
LK http://hdl.handle.net/10668/21620
UL http://hdl.handle.net/10668/21620
LA en
NO Riquelme IL, Blanca MA, Moyano EG. Skin-colored papules on the cheeks, acrochordons on the axillae. Cleve Clin J Med. 2022 Jun 1;89(6):297-299
DS RISalud
RD Aug 8, 2025