TY - JOUR AU - Timsit, Jean-François AU - Bassetti, Matteo AU - Cremer, Olaf AU - Daikos, George AU - de Waele, Jan AU - Kallil, Andre AU - Kipnis, Eric AU - Kollef, Marin AU - Laupland, Kevin AU - Paiva, Jose-Artur AU - Rodríguez-Baño, Jesús AU - Ruppé, Étienne AU - Salluh, Jorge AU - Taccone, Fabio Silvio AU - Weiss, Emmanuel AU - Barbier, François PY - 2019 DO - 10.1007/s00134-019-05520-5 UR - http://hdl.handle.net/10668/13434 T2 - Intensive care medicine AB - The massive consumption of antibiotics in the ICU is responsible for substantial ecological side effects that promote the dissemination of multidrug-resistant bacteria (MDRB) in this environment. Strikingly, up to half of ICU patients receiving... LA - en KW - Antibiotic stewardship KW - Antimicrobial resistance KW - Carbapenem KW - Critical illness KW - Empirical therapy KW - Outcome KW - Sepsis KW - Anti-Infective Agents KW - Antimicrobial Stewardship KW - Humans KW - Intensive Care Units KW - Medical Overuse KW - Rationalization KW - Risk Factors TI - Rationalizing antimicrobial therapy in the ICU: a narrative review. TY - research article VL - 45 ER -