RT Journal Article
T1 Hair Cortisol Concentrations as a Biomarker to Predict a Clinical Pregnancy Outcome after an IVF Cycle: A Pilot Feasibility Study
A1 Santa-Cruz, Diana C.
A1 Caparros-Gonzalez, Rafael A.
A1 Romero-Gonzalez, Borja
A1 Peralta-Ramirez, Maria Isabel
A1 Gonzalez-Perez, Raquel
A1 García-Velasco, Juan Antonio
K1 Infertility
K1 Pregnancy
K1 Cortisol
K1 Stress
K1 Hair
K1 Vitro fertilization
K1 Depression
K1 Hydrocortisone
K1 Infertilidad
K1 Embarazo
K1 Estrés fisiológico
K1 Cabello
K1 Fertilización in vitro
K1 Depresión
K1 Hidrocortisona
AB Our objective was to examine the feasibility of hair cortisol concentrations (HCC) as a biomarker to predict clinical pregnancy outcomes and investigate its potential associations with perceived anxiety, resilience, and depressive symptoms. A total of 43 participants were assessed using HCC, the state trait anxiety inventory (STAI), resilience scale (RS), and the depression subscale of the symptom checklist 90-R (SCL-90-R). Participants were approached at their second consultation with the reproductive endocrinologist (T1), before scheduling their IVF cycle, and then 12 weeks after (T2), at their post-transfer visit with the study coordinators, before the human chorionic gonadotropin (HCG) pregnancy test. The logistic regression model revealed that HCC at T2 predicted 46% of a positive pregnancy test [R2 = 0.46, (ß = 0.11, p < 0.05)]. Pregnant women had higher levels of resilience at T2 (M = 149.29; SD = 17.56) when compared with non-pregnant women at T2 (M = 119.96; SD = 21.71). Significant differences were found between both groups in depression at T2 (t = 3.13, p = 0.01) and resilience at T2 (t = -4.89, p = 0.01). HCC might be a promising biomarker to calculate the probability of pregnancy in women using assisted reproductive technologies (ART).
PB MDPI
SN 1661-7827
YR 2020
FD 2020-04-27
LK http://hdl.handle.net/10668/4250
UL http://hdl.handle.net/10668/4250
LA en
NO Santa-Cruz DC, Caparros-Gonzalez RA, Romero-Gonzalez B, Peralta-Ramirez MI, Gonzalez-Perez R, García-Velasco JA. Hair Cortisol Concentrations as a Biomarker to Predict a Clinical Pregnancy Outcome after an IVF Cycle: A Pilot Feasibility Study. Int J Environ Res Public Health. 2020 Apr 27;17(9):3020
DS RISalud
RD Apr 8, 2025