%0 Journal Article
%A Santa-Cruz, Diana C.
%A Caparros-Gonzalez, Rafael A.
%A Romero-Gonzalez, Borja
%A Peralta-Ramirez, Maria Isabel
%A Gonzalez-Perez, Raquel
%A García-Velasco, Juan Antonio
%T Hair Cortisol Concentrations as a Biomarker to Predict a Clinical Pregnancy Outcome after an IVF Cycle: A Pilot Feasibility Study
%D 2020
%@ 1661-7827
%U http://hdl.handle.net/10668/4250
%X Our objective was to examine the feasibility of hair cortisol concentrations (HCC) as a biomarker to predict clinical pregnancy outcomes and investigate its potential associations with perceived anxiety, resilience, and depressive symptoms. A total of 43 participants were assessed using HCC, the state trait anxiety inventory (STAI), resilience scale (RS), and the depression subscale of the symptom checklist 90-R (SCL-90-R). Participants were approached at their second consultation with the reproductive endocrinologist (T1), before scheduling their IVF cycle, and then 12 weeks after (T2), at their post-transfer visit with the study coordinators, before the human chorionic gonadotropin (HCG) pregnancy test. The logistic regression model revealed that HCC at T2 predicted 46% of a positive pregnancy test [R2 = 0.46, (ß = 0.11, p < 0.05)]. Pregnant women had higher levels of resilience at T2 (M = 149.29; SD = 17.56) when compared with non-pregnant women at T2 (M = 119.96; SD = 21.71). Significant differences were found between both groups in depression at T2 (t = 3.13, p = 0.01) and resilience at T2 (t = -4.89, p = 0.01). HCC might be a promising biomarker to calculate the probability of pregnancy in women using assisted reproductive technologies (ART).
%K Infertility
%K Pregnancy
%K Cortisol
%K Stress
%K Hair
%K Vitro fertilization
%K Depression
%K Hydrocortisone
%K Infertilidad
%K Embarazo
%K Estrés fisiológico
%K Cabello
%K Fertilización in vitro
%K Depresión
%K Hidrocortisona
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