TY  - JOUR
AU  - Cénit, María Carmen
AU  - Márquez, Ana
AU  - Cordero-Coma, Miguel
AU  - Fonollosa, Alejandro
AU  - Llorenç, Victor
AU  - Artaraz, Joseba
AU  - Díaz Valle, David
AU  - Blanco, Ricardo
AU  - Cañal, Joaquín
AU  - Salom, David
AU  - García Serrano, José Luis
AU  - Ramón, Enrique de
AU  - Rio, María José del
AU  - Gorroño-Echebarría, Marina Begoña
AU  - Martín-Villa, José Manuel
AU  - Molins, Blanca
AU  - Ortego-Centeno, Norberto
AU  - Martín, Javier
PY  - 2013
UR  - http://hdl.handle.net/10668/1590
T2  - Molecular vision
AB  - OBJECTIVEEndogenous uveitis is a major cause of visual loss mediated by the immune system. The protein tyrosine phosphatase non-receptor type 22 (PTPN22) gene encodes a lymphoid-specific phosphatase that plays a key role in T-cell receptor (TCR)...
LA  - en
PB  - Molecular Vision
KW  - Alelos
KW  - Demografía
KW  - Estudios de casos y controles
KW  - Estudios de asociación genética
KW  - Frecuencia génica
KW  - Predisposición genética a la enfermedad
KW  - Proteínas mutantes
KW  - Polimorfismo de nucleótido único
KW  - Proteína tirosina fosfatasa no receptora de tipo 22
KW  - Uveítis anterior
KW  - España
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Mutagenesis::Amino Acid Substitution
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Case-Control Studies
KW  - Medical Subject Headings::Health Care::Population Characteristics::Demography
KW  - Medical Subject Headings::Check Tags::Female
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Gene Frequency
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Genetic Association Studies
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genotype::Genetic Predisposition to Disease
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Check Tags::Male
KW  - Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Aged
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Mutant Proteins
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism, Genetic::Polymorphism, Single Nucleotide
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Intracellular Signaling Peptides and Proteins::Protein Tyrosine Phosphatases, Non-Receptor::Protein Tyrosine Phosphatase, Non-Receptor Type 22
KW  - Medical Subject Headings::Geographicals::Geographic Locations::Europe::Spain
KW  - Medical Subject Headings::Diseases::Eye Diseases::Uveal Diseases::Uveitis::Panuveitis::Uveitis, Anterior
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Alleles
TI  - Lack of association between the protein tyrosine phosphatase non-receptor type 22 R263Q and R620W functional genetic variants and endogenous non-anterior uveitis.
TY  - research article
ER  -