RT Journal Article
T1 Incidence, Risk Factors and Outcomes of Early Acute Kidney Injury After Heart Transplantation: An 18-year Experience.
A1 García-Gigorro, Renata
A1 Renes-Carreño, Emilio
A1 Corres Peiretti, María Angélica
A1 Arribas López, Primitivo
A1 Perez Vela, Jose Luis
A1 Gutierrez Rodríguez, Julián
A1 Delgado, Juan Francisco
A1 Cortina Romero, Jose María
A1 Montejo González, Juan Carlos
AB Little is known about the incidence of acute kidney injury (AKI), as defined using the Kidney Disease Improving Global Outcome classification, after heart transplantation (HT). Our objective was to evaluate the impact of AKI in a cohort of HT recipients. (Setting: University Hospital.) METHODS: We studied 310 consecutive HT recipients from 1999 to 2017, with AKI being defined according to the Kidney Disease Improving Global Outcome criteria. Risk factors were analyzed by multivariable analyses, and survival by Kaplan-Meier curves and a risk-adjusted Cox proportional hazards regression model. One hundred twenty-five (40.3%) patients developed AKI, with 73 (23.5%), 18 (5.8%), and 34 (11%) patients having AKI stages 1, 2, and 3, respectively. Cardiac tamponade (odds ratio [OR], 16.82; 95% confidence interval [CI], 1.06-138), acute right ventricular failure (OR, 3.54; 95% CI, 1.82-6.88), and major bleeding (OR, 2.46; 95% CI, 1.18-5.1) were the principal risk factors for AKI. Patients with AKI had a greater hospital mortality (3.8% vs 16%, P  The onset of AKI after HT is mainly associated with postoperative complications. Only severe AKI stage predicts worse short-term outcome, with this impact appearing to be lost at long-term follow-up.
YR 2018
FD 2018
LK https://hdl.handle.net/10668/25409
UL https://hdl.handle.net/10668/25409
LA en
DS RISalud
RD Apr 17, 2025