RT Journal Article T1 Association of cardiovascular emerging risk factors with acute coronary syndrome and stroke: A case-control study A1 Martinez Linares, Jose Manuel A1 Guisado Barrilao, Rafael A1 Ocana Peinado, Francisco Manuel A1 Salgado Parreno, Francisco Javier K1 acute coronary syndrome K1 cardiovascular disease K1 case-control study K1 risk factor K1 stroke K1 Plasma protein-a K1 Natriuretic-peptide K1 Inflammation K1 Morbidity K1 Mortality K1 Disease AB In this study, we estimated the risk of acute coronary syndrome and stroke associated with several emerging cardiovascular risk factors. This was a case-control study, where an age - and sex-matched acute coronary syndrome group and stroke group were compared with controls. Demographic and clinical data were collected through patient interviews, and blood samples were taken for analysis. In the bivariate analysis, all cardiovascular risk factors analyzed showed as predictors of acute coronary syndrome and stroke, except total cholesterol and smoking. In the multivariate logistic regression model for acute coronary syndrome, hypertension and body mass index, N-terminal section brain natriuretic peptide and pregnancy-associated plasma protein-A were independent predictors. For stroke, the predictors were hypertension, diabetes mellitus, body mass index, and N-terminal section brain natriuretic peptide. Controlling for age, sex, and classical cardiovascular risk factors, N-terminal section brain natriuretic peptide and pregnancy-associated plasma protein-A were independent emerging cardiovascular risk factors for acute coronary syndrome, but pregnancy-associated plasma protein-A was not for stroke. High levels of cardiovascular risk factors in individuals with no episodes of cardiovascular disease requires the implementation of prevention programs, given that at least half of them are modifiable. PB Wiley SN 1441-0745 YR 2016 FD 2016-12-01 LK http://hdl.handle.net/10668/18995 UL http://hdl.handle.net/10668/18995 LA en DS RISalud RD Apr 11, 2025