TY - JOUR AU - Cárdenas, Casimiro AU - Torres-Vargas, José Antonio AU - Cárdenas-Valdivia, Abel AU - Jurado, Nuria AU - Quesada, Ana R. AU - García-Caballero, Melissa AU - Martínez-Poveda, Beatriz AU - Medina, Miguel Ángel PY - 2021 DO - 10.1016/j.biopha.2021.112263 SN - 0753-3322 UR - http://hdl.handle.net/10668/4594 T2 - Biomedicine & Pharmacotherapy AB - The tropical plant Annona muricata has been widely used for traditional ethnobotanic and pharmacologic applications. Extracts from different parts of this plant have been shown to have a wide range of biological activities. In the present study, we... LA - en PB - Elsevier Masson SAS KW - Ultra-high-performance liquid KW - Chromatography-high-resolution mass spectrometry (UHPLC–HRMS) KW - Annona muricata KW - Graviola KW - Soursop KW - Angiogenesis KW - Cromatografía líquida de alta presión KW - Espectrometría de masas KW - Annonaceae KW - Annona KW - Neovascularización fisiológica KW - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Growth Substances::Angiogenesis Modulating Agents::Angiogenesis Inhibitors KW - Medical Subject Headings::Organisms::Eukaryota::Animals KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Artiodactyla::Ruminants::Cattle KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Differentiation KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Movement KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Chemistry Techniques, Analytical::Chromatography::Chromatography, Liquid::Chromatography, High Pressure Liquid KW - Medical Subject Headings::Anatomy::Cells::Epithelial Cells::Endothelial Cells KW - Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Metabolome KW - Medical Subject Headings::Phenomena and Processes::Circulatory and Respiratory Physiological Phenomena::Cardiovascular Physiological Phenomena::Cardiovascular Physiological Processes::Neovascularization, Physiologic KW - Medical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Phytochemicals KW - Medical Subject Headings::Chemicals and Drugs::Complex Mixtures::Biological Products::Plant Preparations::Plant Extracts KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Chemistry Techniques, Analytical::Mass Spectrometry::Spectrometry, Mass, Electrospray Ionization KW - Medical Subject Headings::Organisms::Eukaryota::Plants::Viridiplantae::Streptophyta::Embryophyta::Angiosperms::Annonaceae::Annona TI - Non-targeted metabolomics characterization of Annona muricata leaf extracts with anti-angiogenic activity TY - research article ER -