TY - JOUR AU - del Carmen Alamo, Ma AU - Ochenduszko, Sebastian AU - Crespo, Guillermo AU - Corral, Monica AU - Oramas, Juana AU - Sancho, Pilar AU - Medina, Javier AU - Garicano, Fernando AU - Lopez, Pedro AU - Campos Balea, Begona AU - Rodriguez Garzotto, Analia AU - Munoz-Couselo, Eva PY - 2021 DO - 10.2147/OTT.S325208 SN - 1178-6930 UR - https://hdl.handle.net/10668/26599 T2 - Oncotargets and therapy AB - Background: The combination of BRAF and MEK inhibitors delays the onset of resistance and provides more sustained and dramatic responses in comparison with a BRAF inhibitor in monotherapy. The objective of the study was to evaluate the effectiveness... LA - en PB - Dove medical press ltd KW - vemurafenib KW - cobimetinib KW - BRAF KW - metastatic melanoma KW - durable response KW - clinical practice KW - Combination KW - Mortality KW - Outcomes KW - Therapy KW - Cohort KW - V600e TI - Durable Response to Vemurafenib and Cobimetinib for the Treatment of BRAF-Mutated Metastatic Melanoma in Routine Clinical Practice TY - research article VL - 14 ER -