TY  - JOUR
AU  - Segovia-Zafra, Antonio
AU  - Di Zeo-Sánchez, Daniel E.
AU  - López-Gómez, Carlos
AU  - Pérez-Valdés, Zeus
AU  - García-Fuentes, Eduardo
AU  - Andrade, Raúl J.
AU  - Lucena, M. Isabel
AU  - Villanueva-Paz, Marina
PY  - 2021
DO  - 10.1016/j.apsb.2021.11.013
UR  - http://hdl.handle.net/10668/4120
T2  - Acta Pharmaceutica Sinica B
AB  - Idiosyncratic drug-induced liver injury (iDILI) encompasses the unexpected harms that prescription and non-prescription drugs, herbal and dietary supplements can cause to the liver. iDILI remains a major public health problem and a major cause of drug...
LA  - en
PB  - Elsevier BV
KW  - Drug-induced liver injury
KW  - Preclinical models
KW  - Mechanisms
KW  - Oxidative stress
KW  - Mitochondrial damage
KW  - Immune response
KW  - Personalized medicine
KW  - Enfermedad hepática inducida por sustancias y drogas
KW  - Estrés oxidativo
KW  - Inmunidad
KW  - Medicina de precisión
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals
KW  - Medical Subject Headings::Health Care::Environment and Public Health::Public Health
KW  - Medical Subject Headings::Chemicals and Drugs::Pharmaceutical Preparations::Nonprescription Drugs
KW  - Medical Subject Headings::Technology and Food and Beverages::Food and Beverages::Food::Dietary Supplements
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Models, Theoretical
KW  - Medical Subject Headings::Health Care::Health Care Facilities, Manpower, and Services::Health Services::Pharmaceutical Services::Prescriptions
KW  - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Biological Markers::Biomarkers, Pharmacological
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis
TI  - Preclinical models of idiosyncratic drug-induced liver injury (iDILI): Moving towards prediction
TY  - review article
ER  -