RT Journal Article
T1 Generation of a human iPS cell line (CABi003-A) from a patient with age-related macular degeneration carrying the CFH Y402H polymorphism.
A1 Garcia-Delgado, Ana B
A1 Calado, Sofia M
A1 Valdes-Sanchez, Lourdes M
A1 Montero-Sanchez, Adoracion
A1 Ponte-Zuñiga, Beatriz
A1 de la Cerda, Berta
A1 Bhattacharya, Shom Shanker
A1 Diaz-Corrales, Francisco J
AB Age-related macular degeneration (AMD) is the leading cause of adult blindness in developed countries and is characterized by progressive degeneration of the macula, the central region of the retina. A human induced pluripotent stem cell (hiPSC) line was derived from peripheral blood mononuclear cells (PBMCs) from a patient with a clinical diagnosis of dry AMD carrying the CFH Y402H polymorphism. Sendai virus was using for reprogramming and the pluripotent and differentiation capacity of the cells were assessed by immunocytochemistry and RT-PCR.
YR 2019
FD 2019-05-29
LK http://hdl.handle.net/10668/14092
UL http://hdl.handle.net/10668/14092
LA en
DS RISalud
RD Apr 7, 2025