%0 Journal Article
%A Ruiz-de-León, María J
%A Jiménez-Sousa, María A
%A Moreno, Santiago
%A García, Marcial
%A Gutiérrez-Rivas, Mónica
%A León, Agathe
%A Montero-Alonso, Marta
%A González-García, Juan
%A Resino, Salvador
%A Rallón, Norma
%A Benito, José M
%A Vallejo, Alejandro
%A ECRIS Network integrated in the Spanish AIDS Research Network
%T Lower expression of plasma-derived exosome miR-21 levels in HIV-1 elite controllers with decreasing CD4 T cell count.
%D 2018
%U http://hdl.handle.net/10668/12921
%X Exosome-derived miR-21 was independently associated with CD4 T cell decline in HIV-1-infected elite controllers (OR 0.369, 95% CI 0.137-0.994, p = 0.049). Also, a negative correlation between miR-21 expression and MCP-1 level was found (r = -0.649, p = 0.020), while no correlation between soluble biomarkers or cellular immune activation was found.
%K Elite controllers
%K Exosomes
%K HIV-1
%K Immune activation
%K Soluble biomarkers
%K miRNAs
%~