TY - JOUR AU - Aterido, Adria AU - Cañete, Juan D AU - Tornero, Jesus AU - Blanco, Francisco AU - Fernandez-Gutierrez, Benjamin AU - Perez, Carolina AU - Alperi-Lopez, Mercedes AU - Olive, Alex AU - Corominas, Hector AU - Martinez-Taboada, Victor AU - Gonzalez, Isidoro AU - Fernandez-Nebro, Antonio AU - Erra, Alba AU - Lopez-Lasanta, Maria AU - Lopez-Corbeto, Mireia AU - Palau, Núria AU - Marsal, Sara AU - Julia, Antonio PY - 2019 DO - 10.3389/fimmu.2019.01459 UR - http://hdl.handle.net/10668/14246 T2 - Frontiers in immunology AB - Background: Rheumatoid arthritis (RA) is the most frequent autoimmune disease involving the joints. Although anti-TNF therapies have proven effective in the management of RA, approximately one third of patients do not show a significant clinical... LA - en PB - Frontiers Research Foundation KW - Anti-TNF therapy KW - Genomics KW - Multi-omics association analysis KW - Rheumatoid arthritis KW - Transcriptomics KW - Adalimumab KW - Antirheumatic Agents KW - Arthritis, Rheumatoid KW - Biopsy KW - Cohort Studies KW - Female KW - Gene Regulatory Networks KW - Genome-Wide Association Study KW - Humans KW - Infliximab KW - Male KW - Polymorphism, Single Nucleotide KW - Synovial Membrane KW - Transcriptome KW - Treatment Outcome KW - Tumor Necrosis Factor-alpha TI - A Combined Transcriptomic and Genomic Analysis Identifies a Gene Signature Associated With the Response to Anti-TNF Therapy in Rheumatoid Arthritis. TY - research article VL - 10 ER -