TY  - JOUR
AU  - Altea-Manzano, Patricia
AU  - Vandekeere, Anke
AU  - Edwards-Hicks, Joy
AU  - Roldan, Mar
AU  - Abraham, Emily
AU  - Lleshi, Xhordi
AU  - Guerrieri, Ania Naila
AU  - Berardi, Domenica
AU  - Wills, Jimi
AU  - Junior, Jair Marques
AU  - Pantazi, Asimina
AU  - Acosta, Juan Carlos
AU  - Sanchez-Martin, Rosario M
AU  - Fendt, Sarah-Maria
AU  - Martin-Hernandez, Miguel
AU  - Finch, Andrew J
PY  - 2022
DO  - 10.1016/j.molcel.2022.10.005
UR  - http://hdl.handle.net/10668/22394
T2  - Molecular cell
AB  - Inhibition of the electron transport chain (ETC) prevents the regeneration of mitochondrial NAD+, resulting in cessation of the oxidative tricarboxylic acid (TCA) cycle and a consequent dependence upon reductive carboxylation for aspartate synthesis....
LA  - en
KW  - anaplerosis
KW  - cancer
KW  - cancer metabolism
KW  - metabolism
KW  - mitochondrion
KW  - redox
KW  - redox transfer
KW  - respiration
KW  - NAD
KW  - Malate Dehydrogenase
KW  - Oxidation-Reduction
KW  - Citric Acid Cycle
KW  - Respiration
TI  - Reversal of mitochondrial malate dehydrogenase 2 enables anaplerosis via redox rescue in respiration-deficient cells.
TY  - research article
VL  - 82
ER  -