RT Journal Article
T1 Quality of Dietary Fat Intake and Body Weight and Obesity in a Mediterranean Population: Secondary Analyses within the PREDIMED Trial.
A1 Beulen, Yvette
A1 Martínez-González, Miguel A
A1 van de Rest, Ondine
A1 Salas-Salvadó, Jordi
A1 Sorlí, José V
A1 Gómez-Gracia, Enrique
A1 Fiol, Miquel
A1 Estruch, Ramón
A1 Santos-Lozano, José M
A1 Schröder, Helmut
A1 Alonso-Gómez, Angel
A1 Serra-Majem, Luis
A1 Pintó, Xavier
A1 Ros, Emilio
A1 Becerra-Tomas, Nerea
A1 González, José I
A1 Fitó, Montserrat
A1 Martínez, J Alfredo
A1 Gea, Alfredo
K1 body weight
K1 cohort study
K1 fat
K1 obesity
K1 substitution models
AB A moderately high-fat Mediterranean diet does not promote weight gain. This study aimed to investigate the association between dietary intake of specific types of fat and obesity and body weight. A prospective cohort study was performed using data of 6942 participants in the PREDIMED trial, with yearly repeated validated food-frequency questionnaires, and anthropometric outcomes (median follow-up: 4.8 years). The effects of replacing dietary fat subtypes for one another, proteins or carbohydrates were estimated using generalized estimating equations substitution models. Replacement of 5% energy from saturated fatty acids (SFA) with monounsaturated fatty acids (MUFA) or polyunsaturated fatty acids (PUFA) resulted in weight changes of -0.38 kg (95% Confidece Iinterval (CI): -0.69, -0.07), and -0.51 kg (95% CI: -0.81, -0.20), respectively. Replacing proteins with MUFA or PUFA decreased the odds of becoming obese. Estimates for the daily substitution of one portion of red meat with white meat, oily fish or white fish showed weight changes up to -0.87 kg. Increasing the intake of unsaturated fatty acids at the expense of SFA, proteins, and carbohydrates showed beneficial effects on body weight and obesity. It may therefore be desirable to encourage high-quality fat diets like the Mediterranean diet instead of restricting total fat intake.
YR 2018
FD 2018-12-19
LK http://hdl.handle.net/10668/13341
UL http://hdl.handle.net/10668/13341
LA en
DS RISalud
RD Apr 9, 2025