RT Journal Article
T1 Surgical outcomes in the pheochromocytoma surgery. Results from the PHEO-RISK STUDY.
A1 Araujo-Castro, Marta
A1 García Centero, Rogelio
A1 López-García, María-Carmen
A1 Álvarez Escolá, Cristina
A1 Calatayud Gutiérrez, María
A1 Blanco Carrera, Concepción
A1 De Miguel Novoa, Paz
A1 Valdés Gallego, Nuria
A1 Hanzu, Felicia A
A1 Gracia Gimeno, Paola
A1 Fernández-Ladreda, Mariana Tomé
A1 Percovich Hualpa, Juan Carlos
A1 Mora Porta, Mireia
A1 Lorca Álvaro, Javier
A1 Pian, Héctor
A1 Caracuel, Ignacio Ruz
A1 Sanjuanbenito Dehesa, Alfonso
A1 Gómez Dos Santos, Victoria
A1 Serrano Romero, Ana
A1 Oliveira, Cristina Lamas
K1 Clavien-Dindo classification
K1 Pheochromocytoma
K1 Postsurgical complications
K1 Presurgical management
K1 Prolonged hypotension
K1 Urine free metanephrines
AB To identify presurgical and surgical risk factors for postsurgical complications in the pheochromocytoma surgery. A retrospective study of pheochromocytomas submitted to surgery in ten Spanish hospitals between 2011 and 2021. Postoperative complications were classified according to Clavien-Dindo scale. One hundred and sixty-two surgeries (159 patients) were included. Preoperative antihypertensive blockade was performed in 95.1% of the patients, being doxazosin in monotherapy (43.8%) the most frequent regimen. Patients pre-treated with doxazosin required intraoperative hypotensive treatment more frequently (49.4% vs 25.0%, P = 0.003) than patients treated with phenoxybenzamine, but no differences in the rate of intraoperative and postsurgical complications were observed. However, patients treated with phenoxybenzamine had a longer hospital stay (12.2 ± 11.16 vs 6.2 ± 6.82, P  Preoperative medical treatment and postsurgical monitoring of pheochromocytoma should be especially careful in patients with diabetes, cerebrovascular disease, higher levels of plasma glucose and urine free metanephrine and norepinephrine, and with pheochromocytomas >5 cm, due to the higher risk of postsurgical complications.
YR 2021
FD 2021-08-09
LK http://hdl.handle.net/10668/18353
UL http://hdl.handle.net/10668/18353
LA en
DS RISalud
RD Apr 7, 2025